- 1-(Aminoalkyl)-6-aryl;-4H-s-triazole[4,3-a][1,4]benzodiazepines with antianxiety and antidepressant activity
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A series of 1-(Aminoalkyl)-6-aryl;-4H-s-triazole[4,3-a][1,4]benzodiazepines has been prepared and evaluated for central nervous system activity. The authors have found that members of this series have activity in pharmacological test systems designed to detect both anxiolytic and antidepressant activity. Each type of activity could be varied independently by appropriate substituent selections.
- Hester Jr.,Rudzik,Von Voigtlander
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p. 392 - 402
(2007/10/02)
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- Preparation of 1-(2-phthalimidoethyl)-4H-s-tiazolo[4,3-a][1,4]benzodiazepines
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A process for the production of compounds of the formula III: SPC1 wherein ring A is unsubstituted or substituted by fluoro, chloro, bromo, trifluoromethyl, or nitro, and wherein Ar is phenyl, o-chlorophenyl, o-fluorophenyl, or 2-pyridyl, is claimed in wh
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