- Synthesis of uniformly 13C-labeled polycyclic aromatic hydrocarbons
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Convergent synthetic pathways were devised for efficient synthesis of a series of uniformly 13C labeled polycyclic aromatic hydrocarbons de novo from U-13C-benzene and other simple commercially-available 13C-starting compounds. All target products were obtained in excellent yields, including the alternant PAH U-13C-naphthalene, U-13C-phenanthrene, U-13C-anthracene, U- 13C-benz[a]anthracene, U-13C-pyrene and the nonalternant PAH U-13C-fluoranthene.
- Zhang, Zhenfa,Sangaiah, Ramiah,Gold, Avram,Ball, Louise M.
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p. 5431 - 5435
(2011/09/14)
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- Synthesis of naphthalenes and 2-naphthols by the electrophilic cyclization of alkynes
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A wide variety of substituted naphthalenes are readily prepared regioselectively under mild reaction conditions by the 6-endo-dig electrophilic cyclization of appropriate arene-containing propargylic alcohols by IC1, I 2, Br2, NBS, and PhSeBr. 3-Iodo-2-naphthols have also been prepared in excellent yields by the cyclization of analogous 1-aryl-3-alkyn-2-ones. This methodology readily accommodates various functional groups and has been successfully extended to the synthesis of substituted carbazoles and dibenzothiophenes.
- Zhang, Xiaoxia,Sarkar, Sampa,Larock, Richard C.
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p. 236 - 243
(2007/10/03)
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- Synthesis of fused polycycles by 1,4-palladium migration chemistry
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Novel palladium migration/arylation methodology for the synthesis of complex fused polycycles has been developed, in which one or more sequential Pd-catalyzed intramolecular migration processes involving C-H activation are employed. The chemistry works best with electron-rich aromatics, which is in agreement with the idea that these palladium-catalyzed C-H activation reactions parallel electrophilic aromatic substitution.
- Huang, Qinhua,Campo, Marino A.,Yao, Tuanli,Tian, Qingping,Larock, Richard C.
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p. 8251 - 8257
(2007/10/03)
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- 1,4-Palladium migration via C-H activation, followed by arylation: Synthesis of fused polycycles
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A novel palladium migration/arylation methodology for the synthesis of complex fused polycycles has been developed, in which one or more sequential Pd-catalyzed intramolecular migration processes involving C-H activation are employed. The chemistry works best with electron-rich aromatics, which is in agreement with the idea that these palladium-catalyzed C-H activation reactions parallel electrophilic aromatic substitution. Copyright
- Campo, Marino A.,Huang, Qinhua,Yao, Tuanli,Tian, Qingping,Larock, Richard C.
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p. 11506 - 11507
(2007/10/03)
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