The synthesis of novel cis-α-substituted-β-aminotetralins
Teteralones were converted, in 1 to 3 steps, to α-substituted tetralones. Subsequent reductive amination with ammonium acetate/sodium cyanoborohydride gave the corresponding α-substituted-β-aminotetralins, on a multigram scale, with minimal chromatography for the entire transformation.
Youngman, Mark A.,Willard, Nicole M.,Dax, Scott L.,McNally, James J.
p. 2215 - 2227
(2007/10/03)
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