- Application of chlorodifluoromethane as C1 source for synthesis of amidine compounds
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The invention discloses an application of chlorodifluoromethane as a C1 source for synthesis of amidine compounds. Chlorodifluoromethane can be subjected to quadrupole bond cracking under a mild condition, and valuable amidine compounds can be obtained. Water and a solvent are added in the presence of chlorodifluoromethane, the chlorodifluoromethane can be efficiently cracked into a C1 synthon, and synthesis of the amidine compounds can be realized. The synthesis method uses no transition metal, has the characteristic of being environmentally friendly, is simple to operate and can obtain the amidine compounds by one step.
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Paragraph 0040-0041
(2019/09/17)
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- Intermolecular hydrogen-fluorine interaction in dimolybdenum triply bonded complexes modified by fluorinated formamidine ligands for the construction of 2D- and 3D-networks
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The formamidines ArNHC(H)=N-Ar [Ar = Ph (2a), 4-F-Ph (2b), 3,5-F 2Ph (2c) and 2,6-F2Ph (2d) and R = 2,3,5-F3Ph (2e), 3,4,5-F3Ph (2f), F5Ph (2g) and 4-CF3Ph (2h)] were synthesized and the influence of the introduction of a fluorine or a trifluoromethyl group into the aryl unit on the solid-state structures was investigated. On comparing the experimental data, only marginal differences in the geometrical and electronic features of the diverse substituted species were detected. DFT calculations and X-ray crystallography of 2d-2g revealed that the E-syn-configuration corresponded to the thermodynamically most stable motif of all of the examined formamidines. However, in their solid-state, these ligands showed a range of H...F interactions, which varied depending on the number and position of the fluorine atoms on the aryl group and thus led to interesting solid-state structures. Moreover, compounds 2 were used for the synthesis of the new heteroleptic dimolybdenum triply-bonded complexes, Mo 2[(2a-2c; 2e-f)-H]2(OtBu)4 (3a-3c; 3e-3f). X-ray crystallography of complexes 3c and 3f revealed two different isomers in the solid state: in trans-3c the two formamidines are in one plane, while in cis-3c and cis-3f they are next to each other. The DFT calculations showed only a small distinction in energy between the configurations, which led us to assume that the different configurations were induced by the crystal packing. The specific H...F interactions provided by the different formamidines led to a two-dimensional arrangement for trans-3c and a three-dimensional network for cis-3c and cis-3f.
- Krackl, Sebastian,Inoue, Shigeyoshi,Driess, Matthias,Enthaler, Stephan
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experimental part
p. 2103 - 2111
(2011/07/07)
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