Novel synthesis of 3-amino-2-methylbenzotrifluoride from N-(2-X-5-trifluoromethylphenyl)-S,S-dimethylsulfimide
This invention relates to a novel process for preparing 3-amino-2-methylbenzotrifluoride, and to certain novel intermediates produced by the process. 3-Amino-2-methylbenzotrifluoride is a key intermediate useful in the preparation of valuable therapeutic agents such as, for example, 2-(2-methyl-3-trifluoromethyl)anilino nicotinic acid.
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(2008/06/13)
Novel synthesis of 3-amino-2-methylbenzotrifluoride and the intermediates thereof
This invention relates to a novel process for preparing 3-amino-2-methylbenzotrifluoride from 4-X-substituted-2-methylthiomethylbenzotrifluorides. The former compounds are useful in the preparation of anilino-nicotinic and anilino-anthranilic acids exhibiting analgesic, anti-inflammatory or anti-diarrheal properties. Some of the intermediates are novel per se.
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(2008/06/13)
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