cas 6307-35-3, 2-AMINO-5-BROMO-4-HYDROXY-6-METHYLPYRIMIDINE | Articles data ｜lookchem

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6307-35-3

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NOVEL RING TRANSFORMATION REACTIONS AND THEIR APPLICATIONS TO THE SYNTHESES OF POTENTIAL ANTICANCER HETEROCYCLIC COMPOUNDS
Novel heterocyclic ring trasformation reactions developed recently in our laboratory are described.They include pyrimidine to pyrimidine, pyrimidine to pyridine transformations.Also discussed are novel one-step procedures for conversion of 1,3-dimethyluracil derivatives into the pyridopyrimidine system.Some applications of these novel reactions to the syntheses of compounds of biological interest are also described.
Watanabe, K. A.,Su, T.-L.,Pankiewicz, K. W.,Harada, K.
p. 289 - 307
(2007/10/02)

5-Substituted 2-amino-6-phenyl-4(3H)-pyrimidinones. Antiviral- and interferon-inducing agents
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Wierenga,Skulnick,Stringfellow,Weed,Renis,Eidson
p. 237 - 239
(2007/10/02)

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Chemical Properties

Appearance/Colour :white to off-white powder
Melting Point: 244-246 °C(lit.)
Boiling Point: 280.9 °C at 760 mmHg
Flash Point:123.7 °C
Density: 2.04 g/cm³
Vapor Pressure: 0.00368mmHg at 25°C
Refractive Index: 1.719
PKA: 8.26±0.50(Predicted)
BRN: 4959
PSA: 72.03000
LogP: 1.41650

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