PDE 10a Inhibitors for the Treatment of Type II Diabetes
Disclosed are compounds, compositions and methods for treating Type II diabetes. Such compounds are represented by Formula (I) as follows: wherein R1, R2, L, and Q are defined herein.
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Paragraph 0979; 0980
(2015/01/06)
Investigating the antiproliferative activity of quinoline-5,8-diones and styrylquinolinecarboxylic acids on tumor cell lines
The structure-activity relationships of new quinoline based compounds were investigated. Quinoline-5,8-dione and styrylquinoline scaffolds were used for the design of potentially active compounds. The novel analogues had comparable antiproliferative activ
Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.
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Page/Page column 16
(2008/06/13)
Use of the Kohonen neural network for rapid screening of ex vivo anti-HIV activity of styrylquinolines
Using the Kohonen neural network, the electrostatic potentials on the molecular surfaces of 14 styrylquinoline derivatives were drawn as comparative two-dimensional maps and compared with their known human immunodeficiency virus (HIV)-1 replication blocki