- The participation of Singlet Oxygen in Dye-Sensitized Photooxidation Reaction of Catecholamines
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The photooxidation of catecholamines (adrenaline, noradrenaline and dopamine) sensitized by methylene blue (MB), rose bengal (RB) and fluoresceine (FL) proceed via aminochromes and an indolic pathway.In D2O rate constants of sensitized photooxidation are increased for about 2,7 times over rates in water. 1,3-diphenylisobenzofuran (DPBF), 1,4-diazobicyclooctane (DABCO) and azide anion were more effective inhibitors of the reaction in D2O than in H2O.Superoxide dismutase markedly decreases the rates of photooxidation in H2O and in D2O.Isotope effects and 1O2-quenchers sensitivities indicate that singlet oxygen participates on photooxidation processes of catecholamines.
- Kruk, I.
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p. 607 - 613
(2007/10/02)
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