- Total synthesis of proposed structure of coibamide A, a highly N- and O-methylated cytotoxic marine cyclodepsipeptide
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Total synthesis of the originally proposed structure of coibamide A, a highly N- and O-methylated cytotoxic marine cyclodepsipeptide, has been accomplished by using a [(4+1)+3+3]-peptide fragment-coupling strategy and careful examination and optimization
- He, Wei,Qiu, Hai-Bo,Chen, Yi-Jie,Xi, Jie,Yao, Zhu-Jun
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supporting information
p. 6109 - 6112
(2015/01/09)
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- Synthesis towards microcystins and related toxins
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A general route is described for the preparation of microcystins and nodularins, including new chemistry for the preparation of β-methyl-D-aspartic acid.
- Kim, Hong Yong,Stein, Karin,Toogood, Peter L.
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p. 1683 - 1684
(2007/10/03)
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- Synthesis and Antimitogenic Activities of Four Analogues of Cyclosporin A Modified in the 1-Position
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Cyclosporin A (CSA,1), an immunosuppressive cyclic undecapeptide, contains a unique N-methylated amino acid, (2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(N-methylamino)-6-octenoic acid, called both C-9-ene and MeBmt that
- Rich, Daniel H.,Dhaon, Madhup K.,Dunlap, Brian,Miller, Stephen P. F.
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p. 978 - 984
(2007/10/02)
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