- Oxazolidinone compounds and its use in medicine (by machine translation)
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The invention relates to a benzoxazole compound alkane ketones, and its in the preparation of the prevention and treatment of thromboembolic disease in the application. In particular, the invention relates to the general formula (I)) the compound, among them or their stereoisomers, geometric isomers, tautomers, nitrogen oxide, hydrate, solvate, metabolite, pharmaceutically acceptable salt or prodrug, the variables are defined in the specification. The invention also relates to the general formula (I) compound of formula its stereoisomers, geometric isomers, tautomers, nitrogen oxide, hydrate, solvate, metabolite, pharmaceutically acceptable salt or salt of a prodrug use as pharmaceuticals, in particular as used for the prevention and treatment of thromboembolic disease of use. (by machine translation)
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Paragraph 0166-0167
(2017/11/27)
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- Pyridine ketone compound and its composition and use thereof (by machine translation)
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The invention relates to the field of blood coagulation. In particular, the invention relates to a pyridone compound, or a stereoisomer thereof, tautomers, nitrogen oxide, solvate, metabolite, pharmaceutically acceptable salt or prodrug and pharmaceutical composition containing the compound. The invention also relates to such compounds and pharmaceutical composition preparation method, and they in preparing for the prevention, treatment or alleviation of patient Xa factor relative thromboembolic disease in use. (by machine translation)
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Paragraph 0241; 0243; 0244
(2017/08/25)
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- Discovery of orally available integrin α5β1 antagonists
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Previous research within our laboratories identified the 3-hydroxypyrrolidine scaffold 1 as a new and selective integrin α5β1 inhibitor class which was designed for local administration. Herein the discovery of new orally available integrin α5β1 inhibitor scaffolds for potential systemic treatment is described.
- Zischinsky, Gunther,Osterkamp, Frank,Vossmeyer, Doerte,Zahn, Grit,Scharn, Dirk,Zwintscher, Ariane,Stragies, Roland
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scheme or table
p. 380 - 382
(2010/04/02)
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- A Straightforward Synthesis of Azetidin-3-ylacetic Acid
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The preparation of azetidin-3-ylacetic acid from epichlorohydrin via diethyl 2-[1-(diphenylmethyl)azetidin-3-yl] propane-1,3-dioate is described.
- Carruthers, Nicholas I.,Wong, Shing-Chun,Chan, Tze-Ming
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p. 430 - 431
(2007/10/03)
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