cas 64657-18-7, 1,9-DIDEOXYFORSKOLIN | Articles data ｜lookchem

Welcome to LookChem.com Sign In|Join Free

Article Database

Home > CAS Article list >
64657-18-7

Articles about 64657-18-7Total 2 be found

Article title
Article abstract
Author
Journal number and time
Download

Synthetic transformation of ptychantin into forskolin and 1,9-dideoxyforskolin
Forskolin (1), a highly oxygenated labdane diterpenoid and an activator of adenylate cyclase, has been synthesized in 12 steps and 12% overall yield from ptychantin A (4), which has been isolated from liverwort Ptychanthus striatus in good yield. The 1α-hydroxy group was furnished by stereoselective reduction of the corresponding carbonyl group by sodium in t-BuOH. The 9α-hydroxy group was introduced stereoselectively by epoxidation of Δ9.11-enolether. 1,9-Dideoxyforskolin (2), an inhibitor of glucose transporter, has been synthesized in 8 steps and 37% overall yield. The hydroxy group at C-1 was removed by solid-state thicarbonylimidazolation and subsequent radical cleavage.
Hagiwara, Hisahiro,Takeuchi, Fumihide,Kudou, Masaru,Hoshi, Takashi,Suzuki, Toshio,Hashimoto, Toshihiro,Asakawa, Yoshinori
p. 4619 - 4624
(2007/10/03)

First synthesis of 1,9-dideoxyforskolin from ptychantin A
1,9-Dideoxyforskolin 2 has been synthesized starting from ptychantin A 3.
Hagiwara, Hisahiro,Takeuchi, Fumihide,Hoshi, Takashi,Suzuki, Toshio,Hashimoto, Toshihiro,Asakawa, Yoshinori
p. 2305 - 2306
(2007/10/03)

More Articles about upstream products of 64657-18-7

More Articles about downstream products of 64657-18-7

Chemical Properties

Appearance/Colour :solid
Melting Point: 149-150℃
Boiling Point: 455 °C at 760 mmHg
Flash Point:146.9 °C
Density: 1.12 g/cm3
Solubility:methanol: 28 mg/mL
Storage Temp.:−20°C
Vapor Pressure: 3.43E-10mmHg at 25°C
PSA: 72.83000
LogP: 3.43420

Show more

Global suppliers and manufacturers of 64657-18-7total 11 suppliers on LookChem

Company Name
Business Type
Min Order
FOB Price
Main Products
Contact

Hebei Nengqian Chemical Import and Export Co., LTD
Business Type:Trading Company
Min Order:1 Kilogram
FOB Price:USD $ 9.0-99.0 / Kilogram
Main Products:162
Country:

Henan Allgreen Chemical Co.,Ltd
Business Type:Manufacturers
Min Order:No Data
FOB Price:No Data
Main Products:34
Country:

Hangzhou Fandachem Co.,Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:52
Country:

BOC Sciences
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:41
Country:

shanghai Tauto Biotech Co., Ltd
Business Type:Manufacturers
Min Order:No Data
FOB Price:No Data
Main Products:64
Country:

Zibo Hangyu Biotechnology Development Co., Ltd
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:3500
Country:

HENAN SUNLAKE ENTERPRISE CORPORATION
Business Type:Trading Company
Min Order:100 Kilogram
FOB Price:No Data
Main Products:1
Country:

Wuxi Morality Chemical Co., Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

NovaChemistry
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Alta Vista Phyto Chemicals
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Tebu
Business Type:
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 64657-18-7

About us - Payment - Contact us - Links - Help Center - Disclaimer
SiteMap | Manufacturers | VIP Product | Suppliers | CAS | New CAS | Cas Database | Article Data | Chemical Catalog | Product Name

©2008 LookChem.com,License:ICP NO.:Zhejiang16009103 complaints:service@lookchem.com
[Hangzhou]86-571-87562588,87562561,87562573 Our Legal adviser: Lawyer