- PREPARATION OF GABAPENTIN ENACARBIL INTERMEDIATE
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Allyl 1 {[(α-isobutanoyloxyethoxy)carbonyl]aminomethyl}-1-cyclohexane acetate can be prepared by combining allyl 1-aminomethyl-1-cyclohexane acetate hydrochloride, a polar organic solvent, chloroethyl chloroformate, and an amine base or an inorganic base
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Page/Page column 4
(2010/07/04)
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- USE OF PRODRUGS OF GABA ANALOGS FOR TREATING DISEASES
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Methods of using prodrugs of GABA analogs and pharmaceutical compositions thereof to treat migraine, fibromyalgia, amyotrophic lateral sclerosis, irritable bowel syndrome, social phobia, Parkinson's disease, asthma, cough, or chronic obstructive pulmonary disease, and pharmaceutical compositions of prodrugs of GABA analogs useful in treating migraine, fibromyalgia, amyotrophic lateral sclerosis, irritable bowel syndrome, social phobia, Parkinson's disease, asthma, cough, or chronic obstructive pulmonary disease are disclosed.
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Page/Page column 102; 103
(2008/12/06)
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- USE OF GABAPENTIN AND PREGABALIN PRODRUGS FOR TREATING TINNITUS
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Methods of using prodrugs of gabapentin or pregabalin and pharmaceutical compositions thereof to treat tinnitus, and pharmaceutical compositions of prodrugs of gabapentin or pregabalin useful in treating tinnitus are disclosed.
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Page/Page column 52
(2008/12/05)
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- Treating vulvodynia using prodrugs of GABA analogs
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Methods of using prodrugs of GABA analogs and pharmaceutical compositions thereof to treat vulvodynia in a patient, and pharmaceutical compositions of prodrugs of GABA analogs useful in treating vulvodynia are disclosed.
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Page/Page column 17
(2010/11/26)
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- CRYSTALLINE FORM OF GAMMA-AMINOBUTYRIC ACID ANALOG
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A crystalline form of a gamma-aminobutyric acid analog, and methods of preparing same, are provided.
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Page/Page column 25
(2010/02/11)
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