cas 65547-91-3, ethyl 2-amino-1-hydroxyindole-3-carboxylate | Articles data ｜lookchem

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65547-91-3

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Synthesis and reactivity of N-hydroxy-2-aminoindoles
Catalytic hydrogenation of (2-nitrophenyl)acetonitriles bearing an electron-withdrawing substituent α to the nitrile, using Pd/C and (Ph 3P)4Pd, affords N-hydroxy-2-aminoindoles in good to excellent yields. (Ph3P)4Pd decreases the reduction rate of the intermediate hydroxylamine and acts as a catalyst during the cyclization onto the nitrile.
Belley, Michel,Sauer, Effiette,Beaudoin, Daniel,Duspara, Petar,Trimble, Laird A.,Dubé, Pascal
p. 159 - 162
(2007/10/03)

Synthesis of 2-amino-3-carbethoxy-1-hydroxyindoles
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Munshi,Kohl,De Souza
p. 1145 - 1146
(2007/10/05)

More Articles about upstream products of 65547-91-3

65548-02-9
(+/-)-ethyl cyano(2-nitrophenyl)acetate

More Articles about downstream products of 65547-91-3

6433-72-3
2-amino-1H-indole-3-carboxylic acid ethyl ester

Chemical Properties

Melting Point: 175-176 °C
Boiling Point: 449.0±48.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
PKA: 11.80±0.58(Predicted)
PSA: 77.48000
LogP: 2.21870

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