- Bimetallic organotin(IV) complexes with ferrocene-based azomethines: Synthesis, characterization, semi-empirical study, and antibacterial activity
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A series of bimetallic organotin(IV) complexes with ferrocene-based azomethines (Schiff bases) were synthesized by reacting sodium salt of tranexamic acid, 4-amino butanoic acid, and phenyl alanine with trimethyltin and tributyltin chloride in 1 : 1 molar ratio under inert atmosphere. The synthesized trialkyl organotin complexes condense with formyl ferrocene under inert atmosphere to yield organotin(IV) ferrocenyl Schiff bases. Composition of the organotin(IV) complexes, bonding behavior of donor groups, and structural assignments were studied by elemental analysis, FT-IR, 1H, 13C, 119Sn NMR, and mass spectrometry. The spectral data suggest that the ligand is bidentate, coordinating through oxygens. Spectroscopic techniques reveal distorted tetrahedral geometry in solution for the complexes. As solids, the complexes are trigonal bipyramidal, confirmed by semi-empirical study. Mass spectrometric and elemental analysis data support the solid and solution spectroscopic results. Bioactivity screenings show invitro biological potential.
- Tahira, Khizra,Ali, Saqib,Shahzadi, Saira,Sharma, Saroj K.,Qanungo, Kushal
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experimental part
p. 1871 - 1884
(2012/03/22)
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- Phthalocyanine dyes
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Fluorescent dyes are disclosed which are useful as reporter groups for labeling biomolecules. The silicon phthalocyanine dyes disclosed are preferably water soluble, isomericly pure, possess high quantum yield, and are useful in bioassays.
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Page Sheet 1; 29
(2010/02/08)
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- Competitive intramolecular aminolysis: Relative rates of 5-and 6-membered lactam ring closure
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Methyl 4,5-diaminopentanoate (4,5-Dape Me) undergoes competitive intramolecular aminolysis to 5-aminomethyl-2-pyrrolidinone (L5) and 5-amino-2-piperidinone (L6) in dilute alkaline aqueous solution at 25°C. Use of this single compound provides an ideal case for assessing the relative rates of 5- and 6-membered lactam ring closure. Assessments are also made using the intramolecular aminolysis of pairs of compounds: methyl 2,4-diaminobutanoate (2,4-Dab Me) and methyl 2,5-diaminopentanoate (2,5-Dape Me); methyl 4-aminobutanoate (4-Ab Me) and methyl 5-aminopentanoate (5-Ape Me).
- Patterson, Kevin H.,Depree, Gary J.,Zender, Johannes A.,Morris, Peter J.
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p. 281 - 284
(2007/10/02)
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- HYDROLYSIS OF ESTERS OF N-RETINYLIDENEAMINO ACIDS
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The hydrolysis rate of the ester bond in the molecules of methyl esters of the N-retinylidene derivatives of aliphatic amino acids depends on their chain lengths.The higher reaction rates for the derivatives of γ-aminobutyric and δ-aminovaleric acids are explained by intramolecular catalysis.
- Karpenko, E. P.,Mitsner, B. I.,Zvonkova, E. N.,Evstigneeva, R. P.
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p. 1669 - 1673
(2007/10/02)
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