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66898-62-2

Articles about 66898-62-2Total 3 be found

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Process for the preparation of alkyl and aryl esters of 3'-substituted and 2', 3'-disubstituted 2-anilino-3-pyridinecarboxylic acids
In this disclosure, the synthesis of alkyl and aryl esters of substituted 2-anilino-3-pyridinecarboxylic acids is described. This preparation is performed reacting a previously obtained alkyl or aryl ester of 2-chloro-3-pyridinecarboxylic acid, with 3,2 or 3-substituted aniline.
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(2008/06/13)

[New esters of substituted anilinonicotinic and phenylanthranilic acids]
In the search for new non-steroidal antiinflammatory drugs with low ulcerogenic activity, phthalidyl and pivaloyloxymethyl esters of anilinonicotinic and N-phenylanthranilic acids were synthesized. One of them, the 3-phthalidyl ester of 2-([3-(trifluoromethyl)phenyl]amino)-3-pyridinecarboxylic acid, also named talniflumate, showed lower ulcerogenic activity and toxicity and greater antiinflammatory activity than the niflumic acid.
Los, M.,Boned, J. E.,Piccinali, C.
p. 372 - 385
(2007/10/02)

Phthalidyl 2-(3'-trifluoromethyl-anilino)-pyridine-3-carboxylate and its salts
A new phthalidylic eater of 2-(3'trifluoromethyl-anilino)-pyridine-3-carboxylic acid is prepared by reacting 2-(3'-trifluoromethylanilino)-pyridine-3-carboxylic acid with 3-bromophthalide and an organic base in a reaction medium comprising a solvent selec
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(2008/06/13)

More Articles about upstream products of 66898-62-2

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1605347-63-4
3-oxo-1,3-dihydroisobenzofuran-1-yl 5-chloro-2-((3-(trifluoromethyl)phenyl)amino)nicotinate

Chemical Properties

Appearance/Colour :white to pale yellow crystalline powder
Melting Point: 165-167°C
Boiling Point: 534.572 °C at 760 mmHg
Flash Point:277.099 °C
Density: 1.493 g/cm³
Solubility:Chlorform (Slightly), DMSO (Slightly), Methanol (Slightly)
Storage Temp.:Store at +4°C
Vapor Pressure: 1.67E-11mmHg at 25°C
Refractive Index: 1.625
PKA: 2.72±0.10(Predicted)
Merck: 14,9044
PSA: 77.52000
LogP: 4.94300

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