Selective reduction of barbituric acids using SmI2/H 2O: Synthesis, reactivity, and structural analysis of tetrahedral adducts
Making a mark: Since the 1864 landmark discovery by Adolf von Baeyer, barbituric acids have played a prominent role in organic synthesis. Herein, the first chemoselective monoreduction of barbituric acids to the corresponding hemiaminals is described. The method delivers mono- and bicyclic hemiaminal products by a general single-electron-transfer polarity reversal mechanism. Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://angewandte.org/open.
Szostak, Michal,Sautier, Brice,Spain, Malcolm,Behlendorf, Maike,Procter, David J.
p. 12559 - 12563
(2013/12/04)
Reactions of enaminoketones with CH-acidic compounds (author's transl)
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Eiden,Herdeis
p. 287 - 293
(2007/10/05)
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