- A pregnane steroid from Aglaia lawii and structure confirmation of cabraleadiol monoacetate by X-ray crystallography
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The pregnane steroid, (E)-aglawone, along with four known triterpenes, and a known sterol mixture were isolated from the bark of Aglaia lawii (Wight) Saldanha ex Ramamoorty (Meliaceae). The structural determination/identification was accomplished by a combination of 1D- and 2D-NMR spectroscopic techniques. The relative stereochemistry of the known triterpene, 20S,24S-epoxydammarane-3α, 25-diol acetate, was also unequivocally determined for the first time by X-ray crystallography. The isolates were not active against various human cancer cell lines.
- Qiu, Sheng-Xiang,Van Hung, Nguyen,Xuan, Le Thi,Gu, Jian-Qiao,Lobkovsky, Emil,Khanh, Tran Cong,Soejarto, Djaja D.,Clardy, Jon,Pezzuto, John M.,Dong, Yumi,Tri, Mai Van,Huong, Le Mai,Fong, Harry H.S.
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- DAMMARANE TRITERPENES FROM THE STEM BARK OF COMMIPHORA DALZIELLI
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From the stem bark of Commiphora dalzielii the isolation and identification of the 20,24-epoxydammarane triterpenes cabraleadiol 3-acetate, cabraleadiol and cabraleone and isofouquierone are reported.Both the acetate and isofouquierone appear to be novel.The chemotaxonomic implications of findings this type of triterpene in the Burseraceae are discussed.Key Word Index - Commiphora dalzielii; Burseraceae; dammaranes; cabraleadiol; cabraleadiol 3-acetate; cabraleone; isofouquierone; chemical taxonomy.
- Waterman, Peter G.,Ampofo, Stephen
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p. 2925 - 2928
(2007/10/02)
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- TRITERPENOIDS FROM THE LEAVES OF Betula lanata
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From the unsaponifiable fraction of an ethereal extract of the leaves of Betula lanata, in addition to 3-epiocotillol (I) we have isolated a new triterpene, 20(S),24(R)-epoxydammarane-3α,11α,25-triol (V) and also derivatives of it - the monoacetates at C-3 (II) and C-11 (III), and the monoketone at C-3 (IV).The structures of compounds (I-V) have been established on the basis of the results of physicochemical investigations.
- Pokhilo, N. D.,Malinovskaya, G. V.,Makhan'kov, V. V.,Anufriev, V. F.,Uvarova, N. I.
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p. 368 - 372
(2007/10/02)
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