- Synthesis and heterocyclization of β-aroyl-α- diphenylphosphorylpropionic acids
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It has been established that diphenylphosphine oxide reacts smoothly with β-aroylacrylic acids with the formation of β-aroyl-α- diphenylphosphorylpropionic acids, which were cyclized under the action of hydroxylamine, hydrazine hydrate, and phenylhydrazin
- Khachatryan,Khachikyan,Karamyan,Panosyan,Indzhikyan
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p. 446 - 451
(2007/10/03)
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- PHOSPHINYLALKANOYL SUBSTITUTED 4,5-DIHYDROPYRAZOLE-5-CARBOXYLIC ACID DERIVATIVES AND HYPOTENSIVE METHOD AND COMPOSITION
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Compounds of the formula STR1 are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity.
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- Mercaptoacyldihydropyrazole carboxylic acid derivatives
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Hypertension can be treated using compounds having the formula or a basic salt thereof, wherein R1 is hydrogen, alkyl, aryl, arylalkyl or STR1 wherein R5 is alkyl or aryl; R2 is hydrogen or alkyl; R3 is aryl; R4 is hydrogen, alkyl or arylalkyl and n is 0, 1 or 2.
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