The present invention provides compounds, compositions thereof, and methods of using the same.
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Paragraph 0729
(2020/01/12)
PYRROLE mTORC INHIBITORS AND USES THEREOF
The present invention provides compounds, compositions thereof, and methods of using the same.
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Paragraph 00399
(2018/05/27)
SPIRO-SUBSTITUTED OXINDOLE DERIVATIVES HAVING AMPK ACTIVITY
The present invention relates to compounds of formula (I), which have valuable pharmacological properties, in particular are activators of AMPK and which are therefore useful in the treatment of certain disorders that can be prevented or treated by activation of this receptor. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.
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Page/Page column 85
(2015/01/07)
OLEFIN SUBSTITUTED OXINDOLES HAVING AMPK ACTIVITY
The present invention relates to compounds of formula (I), which have valuable pharmacological properties, in particular are activators of AMPK and which are therefore useful in the treatment of certain disorders that can be prevented or treated by activation of this receptor. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.
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Page/Page column 73
(2015/01/07)
Synthesis and DNA Binding Properties of a 4-Hydroxymethylpyrrole-containing Analog of Netropsin
A 4-hydroxymethylpyrrole-containing analog 3 of netropsin has been designed and synthesized. Data from an ethidium bromide displacement assay and CD titration studies showed that it has a preference for the minor groove of AT over GC rich sequences.
Preti, Christopher S.,Simpson, Jacob E.,Lee, Moses
p. 426 - 430
(2007/10/03)
Process for preparing Benzoxepino- or Benzthiapino[4,3-b]pyrrole-2-acetic acids
Improved yields of Benzoxepino- or Benzthiapino[4,3-b]pyrrole-2-acetic acids have been achieved from processes based on modifications performed on a pyrrole carboxylic ester rather than on a pyrrole-α-oxoacetate.
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(2008/06/13)
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