Synthesis and antiproliferative activity of minor hops prenylflavonoids and new insights on prenyl group cyclization
Synthesis of minor prenylflavonoids found in hops and their non-natural derivatives were performed. The antiproliferative activity of the obtained compounds against some human cancer cell lines was investigated. Using xanthohumol isolated from spent hops
Flavonoids as vasorelaxant agents: Synthesis, biological evaluation and quantitative structure activities relationship (QSAR) studies
A series of 2-(2-diethylamino)-ethoxychalcone and 6-prenyl(or its isomers)-flavanones 10a,b and 11a-g were synthesized and evaluated for their vasorelaxant activities against rat aorta rings pretreated with 1 μM phenylephrine (PE). Several compounds showe
Demethylxanthohumol: Isolation from Hops and Cyclisation to Flavanons
Demethylxanthohumol (1) was isolated together with xanthohumol (2) from freshly harvested strobili of hops (humulus lupulus L.).Structure proof of 1 is based on spectroscopic data and on the transformation of 1 and 2 into trimethylxanthohumol (3).Treatmen
Haensel, Rudolf,Schulz, Jutta
p. 37 - 40
(2007/10/02)
Study on the Structure of 5,7,4'-Trihydroxyflavanones
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Mizobuchi, Shigeyuki
p. 2195 - 2196
(2007/10/02)
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