2-(Aminomethyl)phenols, a new class of saluretic agents. 2. Synthesis and pharmacological properties of the 5-aza isostere of 2-(aminomethyl)-4-(1,1-dimethylethyl)-6-iodophenol
2-Halo-4-aminomethyl-6-alkyl-3-pyridinols useful as diuretics in treating hypertension and edema
Certain substituted 4-aminomethyl-3-pyridinols and their pharmaceutically acceptacle acid addition salts wherein the pyridinol nucleus may be further substituted with 1 to 2 nuclear substituents are useful as antihypertensive, diuretic and saluretic agents. These products may be prepared by halogenating an appropriately substituted pyridine salt.
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(2008/06/13)
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