- Gabriel reaction in the synthesis of 2,6-difluorobenzyl amine
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2,6-Difluorobenzyl amine was obtained by Gabriel reaction with a good yield. Intermediate N-(2,6-difluorobenzyl) phthalimide was obtained in the presence of phase transfer catalysts.
- Vasilevskaya, Tamara N.,Yakovleva, Olga D.,Kobrin, Victor S.
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- PROCESS FOR PREPARATION OF HALOGENATED BENZYLAMINE AND INTERMEDIATES THEROF
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The present invention provides an improved process for the preparation of halogenated benzylamine having the formula I from halogenated benzonitriles, Formula I wherein, X1 is selected from group consisting of hydrogen, chloro or fluoro, provided atleast one X1 is chloro or fluoro.
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Page/Page column 18
(2020/08/13)
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- SUBSTITUTED QUINAZOLINE DERIVATIVES AND THEIR USE AS INHIBITORS
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The use of a compound of formula (I) 1 or a salt, ester or amide thereof; where X is O, or S, S(O) or S(O)2, or NR6 where R6 is hydrogen or C1-6 alkyl,; R5 is an optionally substituted 5-membered heteroaromatic ring, R1, R2 ,R3, R4 are independently selected from various specified moieties, in the preparation of a medicament for use in the inhibition of aurora 2 kinase. Certain compounds are novel and these, together with pharmaceutical compositions containing them are also described and claimed
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- Pharmaceutically active triazolopyridine compounds
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This invention describes the preparation and use of anticonvulsant agents. In particular, triazolopyridine compounds are described which have utility in the treatment of epilepsy in mammals.
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- Novel benzylideneaminoguanidines
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This disclosure describes novel substituted benzylideneaminoguanidines useful as anti-hypertensive agents and as diuretics.
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