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70052-12-9

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Catalytic hydrogenation of ethyl 2-amino-2-difluoromethyl-4-cyanobutanoate and its Schiff base reaction modes
Under heterogeneous catalysis, ethyl 2-amino-2-difluoromethyl-4- cyanobutanoate or its Schiff base could be selectively reduced in good yield by hydrogenation to give a diamine, or to form a five-membered ring or a six-membered ring heterocycles. This selectivity is highly dependent on the type of catalysts used.
Zhu, Jingyang,Price, Benjamin A.,Walker, Jonathan,Zhao, Shannon X.
p. 2795 - 2797
(2007/10/03)

2-(Difluoromethyl)-2,5-diaminopentanoic acid
This invention relates to 2-(difluoromethyl)-2,5-diaminopentanoic acid, or a pharmaceutically acceptable acid addition salt thereof, and to the methods for the preparation and use thereof.
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(2008/06/13)

Method of inhibiting the growth of protozoa
α-Substituted amines and α-substituted-α-amino acids are described which are useful in inhibiting the growth of protozoa in animals.
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(2008/06/13)

Method of inhibiting algae
α-Substituted amines and α-substituted-α-amino acids are described which are useful in controlling the growth of algae.
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(2008/06/13)

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Chemical Properties

Melting Point: 138 °C
Boiling Point: 347 °C at 760 mmHg
Flash Point:163.7 °C
Density: 1.293g/cm³
Solubility:H2O: >10 mg/mL, soluble
Storage Temp.:Store at 0°C
Vapor Pressure: 9.72E-06mmHg at 25°C
Refractive Index: 1.462
PKA: 1.22±0.44(Predicted)
PSA: 89.34000
LogP: 1.17310

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