- NOVEL CRYSTALLINE FORM OF TEFLUTHRIN, PROCESS FOR ITS PREPARATION AND USE THEREOF
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Provided are the crystalline form of tefluthrin of formula (I), the crystal preparation process, the analyses of the crystal through various analytical methods and using the crystal to prepare stable agrochemical formulation. Also provided is the use of various solvents towards the crystalline form preparation conditions.
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Paragraph 0069; 0072
(2019/01/05)
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- PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL
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The present invention provides an industrially advantageous process for preparing nuclear halogenated methylbenzyl alcohol which is a useful substance as a raw material, an intermediate for manufacturing medicines, agricultural chemicals, etc. The process of the present invention for preparing nucleus-halogenated methylbenzyl alcohol represented by the following formula (II) comprises hydrogenating nucleus-halogenated benzene carbaldehyde represented by the following formula (I); wherein m is an integer of 0 to 3, and n is an integer of 1 to 4, with the proviso that m+n is an integer of 1 to 4, wherein m and n are the same as those in the formula (I).
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Page/Page column 5
(2010/06/19)
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- Process for producing fluorinated methyl-benzyl alcohol
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An object of the present invention is to provide a process for producing a fluorinated methyl-benzyl alcohol, which process is industrially practicable. A process for producing a fluorinated methyl-benzyl alcohol according to the present invention comprises hydrogenolysis of one hydroxyl group in fluorinated benzene dimethanol.
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- Insecticidal compounds
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The invention provides novel, insecticidally active compounds of formula (I) : wherein X represents a group of formula : where either (i) R1 and R2 represent hydrogen, methyl, halo or haloalkyl, or (ii) R1 represents hydrogen and R2 represents either a group of formula R3(R4)C=CH- or a group of formula R3(R4)(R5)C-CH(R5)-, wherein R3 and R4 represent hydrogen, methyl, halo or haloalkyl and R5 represent chloro or bromo; and Y represents -C≡CR10 or -NH-N=C(R11)R12 where R10, R11 and R12 are selected from hydrogen, alkyl and haloalkyl, or Y represents -CH2Z where Z is selected from halo, CN, N3, CH2CN, -OCOR6, -SCOR7, -OCO2R7, -OR8, -SR8, -N(R15)R8, -OSO2R9 and -ON=C(R13)R14, where R6 represents H, alkyl or haloalkyl, R7 and R9 represent alkyl or haloalkyl, R8 represents propargyl optionally substituted with one or more methyl groups, and R13, R14 and R15 represent alkyl. The invention also provides insecticidal compositions comprising the compounds of formula (I) and methods of controlling insect pests therewith, and processes and intermediates for their preparation.
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- REACTIONS OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA. REACTION OF POLYFLUORINATED DERIVATIVES OF BENZENE WITH SODIUM AMIDE
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Under the influence of sodium amide in liquid ammonia at a temperature no higher than -33 deg C pentafluorobenzene, 1,2,4,5-tetrafluorobenzene, and 1,3-difluorobenzene undergo deprotonation with the formation of fluorinated phenyl anions, which are resistant to the elimination of a fluoride ion and can be detected by the formation of the products from interaction with electrophiles (with the initial compound in the first case and with methyl iodide in the other two cases). 1,3,5-Trifluorobenzene behaves similarly in reaction with one equivalent of sodium amide, but with two equivalents of sodium amide this compound and 1,2,3,5-tetrafluorob enzene undergo substitution of a fluorine atom by an amino group with the formation of 3,5-di- and 3,4,5-trifluoroanilines respectively.This is clearly due to the double deprotonation of these compounds with the formation of polyfluorinated m-phenylene dianions, which are then converted with the elimination of a fluoride ion into the corresponding dehydrophenyl anions.
- Shtark, A. A.,Chuikova, T. V.,Selivanova, G. A.,Shteingarts, V. D.
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p. 2271 - 2276
(2007/10/02)
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- Method of preparing tetrahalobenzene compounds, chemical intermediates used therein and certain of the compounds themselves
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Tetrahalobenzene compounds of the formula (I): STR1 in which X is independently chloro or, preferably, fluoro and Y is hydrogen or --N+ R3 A- in which each R is independently C1-4 alkyl and A is a radical capable of forming an anion A-, are prepared by (a) alkylating a compound of formula (II): STR2 or a salt thereof, to form a compound of formula (III): STR3 (b) treating the compound of formula (III) with a quaternizing agent of formula RA to form a compound of formula (IV): STR4 and (c) partially or completely reductively cleaving the compound of formula (IV) to replace one or both --N+ R3 A- groups by hydrogen. Compounds (I), in which Y is --N+ R3 A-, (III) and (IV) are novel. Compound (I) is useful in the synthesis of insecticides.
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- REACTION OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA IV.* THE NUCLEOPHILIC AND PROTOPHILIC ACTIVITY OF METHOXIDE AND HYDROXIDE IONS IN REACTIONS WITH POLYFLUORINATED AROMATIC COMPOUNDS
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In the reaction of polyfluorinated derivatives of benzene with potassium methoxide in liquid ammonia a fluorine atom is substituted by a methoxy group.With potassium hydroxide reactions involving removal of a proton from a ring carbon atom take place preferentially.The possibility of polyfluoroarylation and methylation catalyzed by potassium hydroxide in polyfluorinated aromatic compounds, based on capture of the polyflurinated aryl anion by the electrophile, was demonstrated.
- Shtark, A. A.,Chuikova, T. V.,Shteingarts, V. D.
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p. 960 - 967
(2007/10/02)
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