Synthesis and Antitumor Activity of Retinoids with Modified Polar Head. Communication I
Several retinoids with a modified polar group were synthesized.Biological screening using HL-60 promyelocyte leukemia cells showed that the free carboxyl in the retinoid molecules is not the only group responsible for exhibiting the differentiating activi
Deryabina, E. L.,Khodonov, A. A.,Cherevataya, G. V.,Kirillova, Yu. G.,Shvets, V. I.,et al.
p. 811 - 818
(2007/10/03)
Potential prophylactic antitumor activity of retinylidene 1,3-diketones
Treatment of all-trans-retinal with a series of 1,3-diketones using Knoevenagel conditions gave the expected condensation products. These retinylidene 1,3-diketones were characterized and their biological activities in the hamster tracheal organ culture t
Acton,Brossi,Newton,Sporn
p. 805 - 809
(2007/10/02)
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