- PIPERAZINE DERIVATIVES AS MAGL INHIBITORS
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The invention provides new heterocyclic compounds having general Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, X, Y1 and Y2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
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Page/Page column 207
(2019/05/02)
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- BENZOIC ACID COMPOUNDS FOR REDUCING URIC ACID
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Uric acid in mammalian subjects is reduced and excretion of uric acid is increased by administering a compound of Formula I. The uric acid-lowering effects of the compounds of this invention are used to treat or prevent a variety of conditions including g
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Paragraph 0270; 0271
(2017/04/11)
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- SPIRO AZETIDINE ISOXAZOLE DERIVATIVES AND THEIR USE AS SSTR5 ANTAGONISTS
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Provided is a compound represented by the following formula (1) or a salt thereof, which has an SSTR5 antagonistic action: wherein each symbol has the same definition as in the specification.
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Paragraph 0671
(2014/09/29)
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- Synthesis and chiral discrimination of cyclic aromatic amides and the determination of their absolute configuration by TD-DFT calculations
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Novel chiral cyclic molecules composed of aromatic triamides were constructed in modest yield from 4-N-(4′-methoxybenzyl)amino-3-decyloxybenzoic acid using dichlorotriphenylphosphorane, because of the preorganized component of the tertiary benzanilide moi
- Katagiri, Kosuke,Ikeda, Takashi,Muranaka, Atsuya,Uchiyama, Masanobu,Tominaga, Masahide,Azumaya, Isao
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scheme or table
p. 2646 - 2650
(2010/03/25)
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- Toward a novel class of antithrombotic compounds with dual function. Discovery of 1,4-benzoxazin-3(4H)-one derivatives possessing thrombin inhibitory and fibrinogen receptor antagonistic activities
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A novel class of potential antithrombotic compounds with moderate thrombin inhibitory and fibrinogen receptor antagonistic activity is described. Combination of anticoagulant and antiaggregatory activity in the same molecular entity is presented as a new
- Anderluh, Petra ?tefani?,Anderluh, Marko,Ila?, Janez,Mravljak, Janez,Dolenc, Marija Sollner,Stegnar, Mojca,Kikelj, Danijel
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p. 3110 - 3113
(2007/10/03)
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- ANTITHROMBOTIC COMPOUNDS WITH DUAL FUNCTION
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The present invention comprises compounds of the general formula (I) : and pharmaceutically acceptable salts thereof, wherein the substituents have in the description specified meaning. The compounds are used as antithrombotic agents possessing inhibitory
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Page/Page column 43-45
(2010/02/11)
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