Solvent-dependent competitive rearrangements of cyclic tertiary propargylamine N-oxides
In protic media, cyclic propargylamine N-oxides 1 undergo solvent-dependent competitive rearrangements leading to enamino aldehydes 5, acrylamides 3, and secondary amines 4. The ratios of the products are evaluated and the possible mechanism of the compet
The stability of butinoline in alkaline and acidic solution was investigated. In alkaline solution the retrosynthesis to benzophenone and 3-pyrrolidino-1-propin was observed, in acidic solution the Meyer-Schuster rearrangement to the corresponding unsaturated amino ketone took place. Thermolysis gave 1,1-diphenyl-2-butin-1-ol in addition to the products of retrosynthesis.
Unterhalt,Middelberg
p. 492 - 494
(2007/10/02)
More Articles about upstream products of 7223-42-9