Synthesis of 4-dialkylamino-and 3-halo-6-methyl-4-methoxy-2-pyranones and their 5,6-dihydro derivatives
A new procedure has been developed for preparation of 4-dialkylamino-6-methyl-2-pyranones and their 5,6-dihydro analogs by reaction of cyclic amines with 4-chloro- and 4-methoxy-2-pyranones. Chlorine and bromine can be introduced into position 3 of the 2-pyranone and 5,6-dihydro-2-pyranone rings via reaction of 4-methoxy derivatives with N-halosuccinimides. In the presence of two equivalents of N-halosuccinimide 3-halo-4-methoxy-6-methyl-5,6-dihydro-2-pyranone is converted into 3-halo-4-methoxy-6-methyl-2-pyranone.
Lokot,Pashkovskii,Lakhvich
p. 1350 - 1354
(2007/10/03)
More Articles about upstream products of 7272-67-5