Impurity profile study of venlafaxine hydrochloride, an antipsychotic drug substance
Venlafaxine hydrochloride is a phenyl ethylamine derivative, used for the treatment of depression. During the process development of venlafaxine hydrochloride, six process-related potential impurities were detected in high-performance liquid chromatograph
Saravanan, Mohanarangam,Kumar, Karra Suresh,Reddy, Padi Pratap,Satyanarayana, Bollikonda
experimental part
p. 1880 - 1886
(2010/09/07)
Simple and an efficient method for the synthesis of 1-[2-dimethylamino-1- (4-methoxy-phenyl)-ethyl]-cyclohexanol hydrochloride: (±) venlafaxine racemic mixtures
A novel synthetic method was developed for the synthesis of venlafaxine using inexpensive reagents. An improvement in the method, in the yield was achieved for the conversion of the venlafaxine. This is an improved version, simple and efficient method for the large-scale synthesis of venlafaxine.
Basappa,Kavitha,Rangappa
p. 3279 - 3281
(2007/10/03)
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