cas 7291-41-0, estra-1,3,5(10),6-tetraene-3,17-diol | Articles data ｜lookchem

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7291-41-0

Articles about 7291-41-0Total 5 be found

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Cytoprotective steroids (II)
A method is provided for treating a patient in need of therapy for acute neuronal degeneration due to metabolic compromise of central or peripheral nervous system cells comprising administering to that patient a therapeutically effective amount of a 7α-hydroxy substituted steroid selected from 7α-hydroxy-derivatives of estradiols, dehydroepiandrosterones and pregnenolones, and metabolic precursors thereof. Use of such compounds for manufacture of medicaments and neuroprotective compositions are also provided.
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(2008/06/13)

New synthesis of Δ6-estrogens
An efficient approach to synthesize Δ6-estrogens is described. The key steps in the synthesis are the introduction of a hydroxyl group at the Δ6 position of a suitably protected estrogen using a superbase and subsequent dehydration with Martin sulfurane reagent or methyltriphenoxyphosphonium iodide. The two-step synthetic procedure readily gave the Δ6-estrogens in high yield.
Rao, Pemmaraju N.,Wang, Zhiqiang
p. 487 - 490
(2007/10/03)

An Efficient Preparation of 6,7-Didehydroestrogenes
The title compounds are prepared in excellent yield by palladium-catalyzed reduction with triethylammonium formate of enol triflates of 6-oxo-estrogens.
Ciattini, Pier Giuseppe,Morera, Enrico,Ortar, Giorgio
p. 1293 - 1297
(2007/10/02)

IMPROVED PREPARATION OF 3,17β-DIHYDROXYOESTRA-1,3,5(10),6-TETRAENE
The title compound is prepared in good yield via the tosylhydrazone of 3,17β-diacetoxyoestra-1,3,5(10)-triene-6-one (Shapiro reaction)
Gill, Julie C.,Marples, Brian A.,Traynor, John R.
p. 155 - 158
(2007/10/02)

Iodoestrogens, syntheses, and interaction with uterine receptors.
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Arunachalam et al.
p. 5900,5904
(2007/10/12)

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Chemical Properties

Melting Point: 210 - 226°C
Boiling Point: 455.1°Cat760mmHg
Flash Point:215.7°C
Density: 1.196g/cm³
Solubility:Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
Storage Temp.:Amber Vial, Refrigerator
Vapor Pressure: 4.49E-09mmHg at 25°C
PSA: 40.46000
LogP: 3.68980

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