One-pot oxidative bromination – Esterification of aldehydes to 2-bromoesters using cerium (IV) ammonium nitrate and lithium bromide
A two-step, one-pot reaction of aldehydes with the CAN/LiBr oxidation system under solvent-free conditions followed by the addition of methanol affords methyl α-bromocarboxylates. The oxidation of aldehydes with methanol using this system gives only methyl esters. A facile method, which does not require special equipment, was developed for the synthesis of 2-bromoesters from aliphatic aldehydes with carbon chain lengths of 5–10 atoms.
Nikishin, Gennady I.,Kapustina, Nadezhda I.,Sokova, Lyubov L.,Bityukov, Oleg V.,Terent'ev, Alexander O.
supporting information
p. 352 - 354
(2017/01/03)
SOLVOLYSIS OF 1-CHLORO-1-ALKENYL PHENYL SULFIDES. SYNTHESIS OF α-BROMO PHENYL THIOCARBOXYLIC ESTERS, α-BROMO ALKYL CARBOXYLIC ESTERS AND α-PHENYLTHIO METHYL CARBOXYLIC ESTERS
1-Chloro-1-alkenyl phenyl sulfides treated with bromine followed by hydrolysis or methanolysis give α-bromo phenyl thiocarboxylic esters and α-phenylthio methyl carboxylic esters.Direct oxidative solvolysis with bromine and alcohol give α-bromo alkyl carboxylic esters.
Fortes, C. C.,Chaves, M. H.
p. 751 - 762
(2007/10/02)
More Articles about upstream products of 7357-56-4