Formation of Inter-nucleotide Bond: Use of Diphenylphosphinothioyl Group as a Protective Group
A convenient method for the preparation of oligonucleotides using diphenylphosphinothioyl group as the protective group for 5'-OH of the ribose moiety of nucleoside is described.The dinucleotides, uridyl (5',3')-adenosine and adenylyl (5',3')-adenosine have been prepared employing this reagent.
Agrawal, Sudhir,Misra, Krishna
p. 132 - 134
(2007/10/02)
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