- Selenophenol quinoline derivative as well as preparation method and application thereof
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The invention discloses a selenophenol quinoline derivative as well as a preparation method and application thereof. The structure of the selenophenol quinoline derivative is shown as a formula I, a formula II or a formula III, wherein R1 is hydrogen, a C1-6 alkyl group, a C1-6 alkoxy group, a substituted ketone group, a phenyl group, a benzyl group, a substituted phenyl group or a substituted benzyl group; R1 is a monovalent metal cation; R2 is one or more of hydrogen, halogen, a C1-4 alkyl group, a C1-4 alkoxy group or a C1-4 haloalkyl group; R3 is a substituted five-membered heterocyclicring or a substituted six-membered heterocyclic ring; and a heteroatom is one or more of N, O, S or Se. The compound disclosed by the invention is novel in structure, simple in preparation process and relatively good in inhibition effect on various cancer cells, particularly the compounds 34, 44, 45, 98, 104, 115 and 116 have excellent inhibition effects on various cancer cells, the effects of the compounds are equivalent to those of a positive control DDP, and the compounds can be used to prepare anti-cancer drugs to be applied under 5 [mu]M or below, so that the prospect is wide.
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Paragraph 0442; 0445-0447
(2020/12/30)
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- 2, 5-SELENOPHENE DERIVATIVES AND 2, 5-TELLUROPHENE DERIVATIVES
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The invention relates to 2,5-selenophene derivatives and 2,5-tellurophene derivatives, inter alia for use as components in liquid-crystal mixtures, and to liquid-crystal mixtures which comprise the compounds, and to liquid-crystal displays based on these mixtures. The invention furthermore relates to processes for the preparation of the compounds and to Se/Te-containing intermediates.
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Page/Page column 50-51
(2010/09/05)
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- Heteroaromatic Rings as Substituents. Part 5. Evaluation of ? and ?- Constants of 2-Selenienyl and 2-Tellurienyl Groups
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p- and m-2-selenienyl- and 2-tellurienyl-anisoles, p- and m-2-selenienyl- and 2-tellurienyl-phenols, and four 2,5-disubstituted tellurophens were synthesized and their structures established by 1H n.m.r. and mass spectra.The ?- and ? constants
- Fringuelli, Francesco,Serena, Bernardino,Taticchi, Aldo
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p. 971 - 975
(2007/10/02)
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