cas 75180-46-0, C-[1-(4-FLUORO-PHENYL)-CYCLOPROPYL]-METHYLAMINE | Articles data ｜lookchem

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75180-46-0

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Lewis Basic Sulfide Catalyzed Electrophilic Bromocyclization of Cyclopropylmethyl Amide
A Lewis basic sulfide catalyzed electrophilic bromocyclization of cyclopropylmethyl amide has been developed. The catalytic protocol is applicable to both 1,1- and 1,2-substituted cyclopropylmethyl amides, giving oxazolines and oxazines in good yields and excellent diastereoselectivity.
Wong, Ying-Chieh,Ke, Zhihai,Yeung, Ying-Yeung
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p. 4944 - 4947
(2015/11/03)

Positive Allosteric Modulators of MGLUR2
The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds modulate the mGluR2 receptor and may be useful for the treatment of various disorders of the centr
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(2013/09/26)

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Chemical Properties

Boiling Point: 232.7±23.0 °C(Predicted)
Density: 1.140±0.06 g/cm3(Predicted)
PKA: 10.36±0.29(Predicted)
PSA: 26.02000
LogP: 2.51630

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