- Copper-catalyzed efficient access to 2,4,6-triphenyl pyridinesviaoxidative decarboxylative coupling of aryl acetic acids with oxime acetates
-
An efficient and concise approach for the synthesis of 2,4,6-triphenyl pyridines has been developed through copper-catalysed oxidative decarboxylative coupling of C(sp3) aryl acetic acids with oxime acetates in DMF at 150 °C under an oxygen atm
- Bharat Kumar, Karasala,Chinnari, Lekkala,Shyamala, Pulipaka,Siddaiah, Vidavalur,Varaprasad, Bodala
-
supporting information
p. 15205 - 15209
(2021/09/06)
-
- Transition-metal-free selective pyrimidines and pyridines formation from aromatic ketones, aldehydes and ammonium salts
-
An efficient synthesis of pyrimidines and pyridines has been developed from readily available aromatic ketones, aldehydes and ammonium salts under transition-metal-free conditions. In this strategy, ammonium salts were used as nitrogen sources and only wa
- Chen, Jinjin,Meng, Huanxin,Zhang, Feng,Xiao, Fuhong,Deng, Guo-Jun
-
supporting information
p. 5201 - 5206
(2019/10/11)
-
- Application of a novel, efficient and recyclable photo redox catalyst (Zn–Al layered double hydroxide/eosin) for the synthesis of substituted pyridine derivatives under visible light irradiation
-
Layered double hydroxides (LDHs) are a class of anionic clays with brucite-like layers and interlayer anions and varying in composition and morphology. LDHs show potential as supports for the immobilization of catalytically active species, to synthesize recyclable catalysts, in which catalytic sites can be preferentially orientated, highly dispersed and stabilized to afford high catalytic efficiency and recyclability in reaction media. Redox active organic dyes such as eosin Y with strong absorption in the visible region of the spectrum have been successfully used. In this work, an intercalated photo redox catalyst (Zn–Al LDH/eosin) was synthesized by co-precipitation of an aqueous solution of zinc nitrate and aluminium nitrate simultaneously with eosin Y as anionic dye. Zn–Al LDH/eosin as a recyclable catalyst was used in the reaction of various aryl ketones and benzylamines under molecular oxygen and visible light, giving good yields of substituted pyridines at room temperature. Also, the Zn–Al LDH/eosin catalyst could be reused three times without any significant changes in the reaction yields.
- Rasouli, Nahid
-
-
- Catalytic application of sulfonic acid-functionalized titana-coated magnetic nanoparticles for the preparation of 1,8-dioxodecahydroacridines and 2,4,6-triarylpyridines via anomeric-based oxidation
-
We have developed green, efficient and powerful protocols for the preparation of 2,4,6-triarylpyridines and 1,8-dioxodecahydroacridines in the presence of Fe3O4@TiO2@O2PO2(CH2)2NHSO3H as a sulfonic acid-functionalized titana-coated magnetic nanoparticle catalyst under mild and solvent-free reaction conditions. These protocols furnished the desired products in short reaction times with good to high yields (20–40?min and 80–86% in the case of 2,4,6-triarylpyridines; 15–90?min and 80–93% in the case of 1,8-dioxodecahydroacridines). The final step of the mechanistic route in the synthesis of 2,4,6-triarylpyridines proceeds via an anomeric-based oxidation. Also, the nanomagnetic core–shell catalyst can be recycled and reused in both cases of the scrutinized one-pot multicomponent reactions with high turnover number and turnover frequency.
- Zolfigol, Mohammad Ali,Karimi, Fatemeh,Yarie, Meysam,Torabi, Morteza
-
-
- Synthesis of 2,4,6-Trisubstituted Pyridines by Oxidative Eosin y Photoredox Catalysis
-
Eosin Y, an organic dye, was activated as a photoredox catalyst in the presence of molecular oxygen using visible light and, when it was used in the reaction of aryl ketones and benzyl amines, afforded good yields (52-87%) of 2,4,6-triarylpyridines (21 examples) at ambient temperature. The aryl groups at the 2- and 6-positions are derived from ketones, while benzyl amine plays the dual role of providing an aryl functionality at the 4-position of pyridine as well as being a nitrogen donor.
- Rohokale, Rajendra S.,Koenig, Burkhard,Dhavale, Dilip D.
-
p. 7121 - 7126
(2016/08/30)
-
- An Efficient Synthesis of 2,4,6-Triarylpyridines by Use of Benzyl Halides under Neat Conditions
-
An efficient synthesis of 2,4,6-triarylpyridines is described. Heating a mixture of an acetophenone, a benzyl halide, and ammonium acetate under neat conditions afforded the corresponding Kr?hnke pyridines in excellent yields.
- Adib, Mehdi,Ayashi, Neda,Mirzaei, Peiman
-
p. 417 - 421
(2016/02/09)
-
- Silica vanadic acid [SiO2-VO(OH)2] as an efficient heterogeneous catalyst for the synthesis of 1,2-dihydro-1-aryl-3H-naphth[1,2-e][1,3]oxazin-3-one and 2,4,6-triarylpyridine derivatives via anomeric based oxidation
-
Silica-bonded vanadic acid [SiO2-VO(OH)2] (SVA) efficiently catalyzed the synthesis of 1,2-dihydro-1-aryl-3H-naphth[1,2-e][1,3]oxazin-3-ones via reacting aromatic aldehydes and β-naphthol and urea under solvent-free condition. Additi
- Zolfigol, Mohammad Ali,Safaiee, Maliheh,Afsharnadery, Fatemeh,Bahrami-Nejad, Neda,Baghery, Saeed,Salehzadeh, Sadegh,Maleki, Farahnaz
-
p. 100546 - 100559
(2015/12/08)
-
- Synthesis of 2,4,6-triarylpyridines using ZrOCl2 under solvent-free conditions
-
An efficient procedure for the synthesis of 2,4,6-triarylpyridines (Kr?hnke pyridines) by the one-pot multicomponent condensation of aldehydes (1 equiv) with acetophenones (2 equiv) and ammonium acetate (1.2 equiv) in the presence of catalytic amounts of
- Moosavi-Zare, Ahmad Reza,Zolfigol, Mohammad Ali,Farahmand, Shohreh,Zare, Abdolkarim,Pourali, Ali Reza,Ayazi-Nasrabadi, Roya
-
p. 193 - 196
(2014/02/14)
-
- Mesoporous nanocrystalline MgAl2O4: A new heterogeneous catalyst for the synthesis of 2,4,6-triarylpyridines under solvent-free conditions
-
In this paper, one-pot synthesis of 2,4,6-triarylpyridine by condensation of subsisted acetophenone (II), aromatic aldehydes (I), and ammonium acetate (III) in the presence of nanocrystalline MgAl2O4 as a new heterogeneous catalyst under solvent-free conditions is reported. Advantages of this method are the use of spatially-hindered aldehydes such as 2-methoxy-, 2-fluoro-, and 2-chlorobenzaldehydes, a new nanocatalyst with high surface area, shorter reaction time, easier workup, higher yield, and its environmental friendliness. The performance of this reaction under solvent free conditions using heterogeneous catalysts like MgAl2O4 could enhance its efficiency from an economic as well as green chemistry point of view.
- Safari, Javad,Zarnegar, Zohre,Borujeni, Mahmoud Borjian
-
p. 688 - 695
(2013/07/26)
-
- Microwave-assisted, solvent-free, three-component synthesis of 2,4,6-triarylpyridines from benign components
-
2,4,6-Triarylpyridine derivatives were synthesised by the reaction of guanidine with an acetophenone and a chalcone. These reactions were carried out as economical one-pot reactions under green conditions: no catalyst and solvent free.
- Zomordbakhsh, Shahab,Anaraki-Ardakani, Hossein,Zeeb, Mohsen,Sadeghi, Mahdi,Mazraeh-Seffid, Manouchehr
-
experimental part
p. 138 - 140
(2012/09/22)
-
- Green, new and efficient tandem oxidation and conversion of aryl alcohols to 2,4,6-triarylpyridines promoted by [HMIm]NO3-[BMIm]BF4 as a binary ionic liquid
-
A novel, clean and efficient tandem process has been established for the synthesis of 2,4,6-triarylpyridines from primary aryl alcohols or 1-arylethanols using 1-methylimidazolium nitrate in 1-butyl-3-methylimidazolium tetrafluoroborate as a binary task-specific ionic liquid under microwave irradiation.
- Khosropour, Ahmad R.,Mohammadpoor-Baltork, Iraj,Kiani, Forough
-
experimental part
p. 441 - 445
(2012/03/22)
-
- Solvent-free, one-pot synthesis of 2,4,6-triarylpyridines using trichloroisocyanuric acid or N-bromosuccinimide as a novel and neutral catalyst
-
A simple and benign protocol has been explored for the preparation of 2,4,6-triarylpyridines by a one-pot reaction between aryl aldehydes, enolizable ketones and ammonium acetate in the presence of N-bromosuccinimide or trichloroisocyanuric acid as green and neutral catalysts. The reactions proceed smoothly at 130 °C under solvent-free conditions to provide 2,4,6-triarylpyridines in good yields.
- Maleki, Behrooz,Salehabadi, Hafezeh,Sepehr, Zeinalabedin,Kermanian, Mina
-
experimental part
p. 1307 - 1315
(2012/04/04)
-
- PEG-400 catalyzed reaction for the synthesis of 2, 4, 6-Triarylpyridines and crystal structure of 2,4,6-tris(4'-chlorophenyl)pyridine
-
An efficient and rapid procedure for synthesizing triarylpyridine compounds under mild reaction conditions has been described. Meanwhile, the crystal structure of 2,4,6-tris(4'-chlorophenyl)pyridine was obtained and determined by X-ray single-crystal diffraction. The procedure is operationally simple, giving good to high product yields.
- He, Qingpeng,Wang, Jianyong,Feng, Ruokun
-
experimental part
p. 172 - 177
(2010/08/07)
-
- Wet 2,4,6-trichloro-1,3,5-triazine (TCT) as an efficient catalyst for the synthesis of 2,4,6-triarylpyridines under solvent-free conditions
-
An efficient one-pot synthesis of 2,4,6-triarylpyridines has been described. This involves the three-component reaction of aldehydes, ketones and ammonium acetate in the presence of a catalytic amount of wet 2,4,6-trichloro-1,3,5-triazine (TCT) under solvent-free condition at 130 °C.
- Maleki, Behrooz,Azarifar, Davood,Veisi, Hojat,Hojati, Seyede Fatemeh,Salehabadi, Hafezeh,Yami, Razieh Nejat
-
experimental part
p. 1346 - 1349
(2011/10/08)
-
- Reaction between guanidine hydroehloride and chalcones: An efficient solvent-free synthesis of 2,4,6-triarylpyridines under microwave irradiation
-
A series of 2,4,6-triarylpyridines have been synthesized via an efficient solvent-free reaction between guanidine hydro-chloride and chalcones under microwave irradiation in excellent yields. Copyright
- Adib, Mehdi,Mohammadi, Bagher,Rahbari, Sahar,Mirzaei, Peiman
-
scheme or table
p. 1048 - 1049
(2009/12/02)
-
- Kr?hnke pyridines: an efficient solvent-free synthesis of 2,4,6-triarylpyridines
-
A simple and efficient synthesis of 2,4,6-triarylpyridines is described from a novel reaction between chalcones and ammonium acetate under solvent-free conditions in excellent yields.
- Adib, Mehdi,Tahermansouri, Hasan,Koloogani, Somayeh Aali,Mohammadi, Bagher,Bijanzadeh, Hamid Reza
-
p. 5957 - 5960
(2007/10/03)
-
- An efficient improve for the kroehnke reaction: One-pot synthesis of 2,4,6-triarylpyridines using raw materials under microwave irradiation
-
A series of 2,4,6-triarylpyridines have been prepared by the one-pot reaction of aldehydes with aromatic ketones in the presence of ammonium acetate under microwave irradiation without catalyst. This method has the advantage of easier workup, shorter reaction time, higher yield, and environment-friendly. Copyright
- Tu, Shujiang,Li, Tuanjie,Shi, Feng,Fang, Fang,Zhu, Songlei,Wei, Xianyong,Zong, Zhimin
-
p. 732 - 733
(2007/10/03)
-
- Studies on Benzopyridinium Ylids: Synthesis of Substituted 2,4,6-Triarylpyridines via Isoquinolinium Ylids
-
Aroylmethylene-isoquinolinium ylids (1) on reaction with substituted benzylideneacetophenones (2) in gl.acetic acid containing ammonium acetate afford 2,4,6-triarylpyridines (4).The reaction seems to proceed via N-(1,5-dioxo-2-pentyl)-isoquinolium derivat
- Tewari, R. S.,Dubey, A. K.,Gupta, K. C.
-
p. 706 - 707
(2007/10/02)
-
- Studies on Cycloimmonium Ylides. Synthesis of Some 2,4,6-Triaryl-Substituted Pyridines via Picolinium Ylides
-
A wide variety of 2,4,6-triaryl-substituted pyridines have been synthesized by the interaction of aroylmethylenepicolinium ylides with different α,β-unsaturated ketones.The structural assignments were based on microanalytical and spectral data.
- Tewari, Ram. S.,Dubey, Ajay K.,Misra, Naresh K.,Dixit, Priya D.
-
p. 106 - 108
(2007/10/02)
-