cas 75945-90-3, Methyl 4-oxo-1-phenylcyclohexanecarboxylate | Articles data ｜lookchem

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75945-90-3

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Cyclohexyl derivatives and their use as therapeutic agents
The present invention relates compounds of the formula (I): wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of: (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), (l) and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R?17, R18, R19, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.
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Page 23

(2010/02/03)

Cyclohexane derivatives and their use as therapeutic agents
The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R17, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.
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Page 20

(2010/02/06)

Synthesis and Reactivity of 4-Phenylisoquinuclidines
Several approaches to the synthesis of the 2-alkyl-4-phenylisoquinuclidines 14 and 15, the 3,4-diphenylisoquinuclidines 22-24 and of 6-oxo-4-phenyl-3-isoquinuclidone (43) are described.The structure of the products of hydrolysis of 7-phenyl-1,4-dioxaspirodecanecarboxamide (36) were determined by spectroscopy and degradative reactions.
Schneider, Woldemar,Krombholz, Gottfried
p. 487 - 498
(2007/10/02)

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Chemical Properties

Boiling Point: 348.336 °C at 760 mmHg
Flash Point:152.881 °C
Density: 1.143 g/cm³
Storage Temp.:2-8°C
Vapor Pressure: 0mmHg at 25°C
Refractive Index: 1.533
PSA: 43.37000
LogP: 2.24050

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