cas 760207-87-2, 5-Bromo-2-methoxy-3-methylpyridine | Articles data ｜lookchem

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760207-87-2

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CARBOXAMIDE AND SULFONAMIDE DERIVATIVES USEFUL AS TEAD MODULATORS
The invention is concerned with the compounds of formula (I) and formula (II): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of using the compounds of formula (I) and formula (II) as well as pharmaceutical compositions containing such compounds. The compounds are useful in treating diseases and conditions mediated by TEAD, such as cancer.
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Paragraph 0426-0431

(2020/03/29)

ANTI-FIBROTIC PYRIDINONES
This application relates to polycyclic compounds with a pyridinone or pyridinone derivative core including, substituted pyridinones, 5,6- and 6,6- bicyclic heterocycles and substituted pyridine-thiones. This application also discloses methods of preparing these polycyclic compounds, pharmaceutical compositions and medicaments comprising said compounds and methods to treat, prevent or diagnose diseases, disorders or conditions associated with fibrosis.
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Paragraph 1120

(2015/11/02)

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Chemical Properties

Boiling Point: 217.784 °C at 760 mmHg
Flash Point:85.513 °C
Density: 1.452 g/cm³
Storage Temp.:Room temperature.
Vapor Pressure: 0.192mmHg at 25°C
Refractive Index: 1.538
PKA: 1.33±0.20(Predicted)
PSA: 22.12000
LogP: 2.16110

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