The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of b3-adrenoceptor. Formula (I).
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(2017/04/21)
CHEMOKING RECEPTOR ANTAGONISTS
Disclosed herein are chemokine receptor antagonists of formula (I) wherein G1, X1, X2, and X3 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.
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(2013/03/26)
A convenient synthesis of (1 H-azol-1-yl)piperidines
A convenient preparation of 3- and 4-(1H-azol-1-yl)piperidines by arylation of azoles (i.e., pyrazoles, imidazoles, and triazoles) with 3- and 4-bromopyridines and subsequent reduction of the pyridine ring was developed. The method was extended to benzo analogues of the title compounds. Georg Thieme Verlag Stuttgart · New York.
Shevchuk, Nadiia V.,Liubchak, Kostiantyn,Nazarenko, Kostiantyn G.,Yurchenko, Aleksandr A.,Volochnyuk, Dmitriy M.,Grygorenko, Oleksandr O.,Tolmachev, Andrey A.
experimental part
p. 2041 - 2048
(2012/08/07)
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