Four different schemes for the synthesis by the classical method of pyroglutamylasparaginylglycine - a suggested aggression peptide have been described.The best is a scheme using C- and N-terminal protective groups of the benzyl type at the stage of obtaining the protected tripeptide.Literature information according to which the compound possesses biological activity has been refuted.
Sorochinskaya, E. I.,Leont'eva, L. I.,Martynov, V. F.