- Rational Design of a Near-infrared Fluorescence Probe for Ca2+ Based on Phosphorus-substituted Rhodamines Utilizing Photoinduced Electron Transfer
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Fluorescence imaging in the near-infrared (NIR) region (650–900 nm) is useful for bioimaging because background autofluorescence is low and tissue penetration is high in this range. In addition, NIR fluorescence is useful as a complementary color window t
- Takahashi, Shodai,Hanaoka, Kenjiro,Okubo, Yohei,Echizen, Honami,Ikeno, Takayuki,Komatsu, Toru,Ueno, Tasuku,Hirose, Kenzo,Iino, Masamitsu,Nagano, Tetsuo,Urano, Yasuteru
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supporting information
p. 524 - 530
(2020/02/05)
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- OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO
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Compounds are provided having the structure of Formula (I): or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein A, B, L, R3, R4, R5, R6, R8, m and n are as defined herein. Such compounds modulate the opioid receptor, particulare the mu-opioid receptor (MOR) and/or the kappa-opioid receptor (KOR), and/or the delta-opioid receptor (DOR). Products containing such compounds, as well as methods for their use and preparation, are also provided.
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Page/Page column 223-224
(2019/10/29)
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- Btk INHIBITORS WITH IMPROVED DUAL SELECTIVITY
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Disclosed herein is a tri-substituted phenyl Btk inhibitors with improved dual selectivity, a method and a composition for inhibiting Btk and treating disease associated with undesirable Btk activity (Btk-related diseases).
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Paragraph 0200-0202
(2019/03/05)
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- NEAR-INFRARED FLUORESCENT CALCIUM PROBE
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PROBLEM TO BE SOLVED: To provide a novel near-infrared fluorescent Ca2+ probe showing a fluorescence rise higher than that of conventional one. SOLUTION: The present invention provides a P rhodamine compound having a calcium ion scavenging grou
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Paragraph 0072; 0073; 0086; 0087
(2018/07/28)
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- QUINAZOLINE DERIVATIVES USED TO TREAT HIV
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Described herein are compounds of Formula (I) and tautomers and pharmaceutical salts thereof, compositions and formulations containing such compounds, and methods of using and making such compounds.
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Paragraph 0339
(2016/07/27)
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- Synthesis and characterization of new tetra-substituted porphyrins with exo-donor carboxylic groups as building blocks for supramolecular architectures. Catalytic and structural studies of their metalated derivatives
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We report herein the synthesis of the porphyrins 5,10,15,20-tetrakis(4- carboxybiphenyl)-porphyrin (H2TCBP) and 5,10,15,20-tetrakis(4- carboxy-2,6-dimethylbiphenyl)porphyrin (H2TCDMBP) bearing diphenyl units on meso-positions, and of
- Carlucci, Lucia,Ciani, Gianfranco,Maggini, Simona,Proserpio, Davide M.,Ragaini, Fabio,Gallo, Emma,Ranocchiari, Marco,Caselli, Alessandro
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experimental part
p. 804 - 814
(2011/09/15)
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