- A practical and economical high-yielding, six-step sequence synthesis of a flavone: Application to the multigram-scale synthesis of ladanein
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Herein we report a short and economic synthesis of the antiviral flavonoid lead ladanein (1). Ladanein is obtained from 2,6-dimethoxyquinone (11) in six steps with 51% overall yield. After a high-yielding reductive acetylation and Fries rearrangement, the
- Martin-Benlloch, Xavier,Elhabiri, Mourad,Lanfranchi, Don Antoine,Davioud-Charvet, Elisabeth
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p. 613 - 617
(2014/06/09)
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- FLAVONE DERIVATIVES AND THEIR USE
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The present invention relates to flavone derivatives and to compositions containing one or more of these flavone derivatives. The present invention further relates to fiavone derivatives or compositions for use in the treatment and/or prevention of a vira
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Page/Page column 34; 35
(2013/10/08)
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- Flavone derivatives and their use
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The present invention relates to flavone derivatives and to compositions containing one or more of these flavone derivatives. The present invention further relates to flavone derivatives or compositions for use in the treatment and/or prevention of a vira
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Paragraph 0092
(2013/10/08)
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- Preparation and properties of chlorinated syringic acids, acetosyringones, acetoguaiacones and methoxy-p-hydroquinones components of pulp bleaching effluents
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A range of chlorinated phenols which serve as standards for compounds occurring in effluents from the bleaching of wood pulps with chlorine-containing reagents has been prepared. The chlorinated phenols include chlorosyringic acids, chloroacetosyringones, chloroacetoguaiacones, 5-chloro-2-methoxy-p-hydroquinone and chloro-2,6-dimethoxy-p-hydroquinones. With the exception of the ring-chlorinated acetoguaiacones which were prepared by reaction of chlorovanillin acetates with diazomethane, the compounds were obtained by direct chlorination of appropriate phenols or their acetates. Gas chromatographic and mass spectrometric data for the acetylated phenols are given.
- Smith,Wearne,Wallis
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