Novel probes for imaging amyloid-β: F-18 and C-11 labeling of 2-(4-aminostyryl)benzoxazole derivatives
2-(4-Methylaminostyryl)-6-(2-[18F]fluoroethoxy)benzoxazole ([18F]BF-168) was prepared and found to be a potential probe for imaging amyloid-β. The precursor, a 6-(2-tosyloxyethoxy)benzoxazole derivative, was fluorinated with [18