Compounds Acting on Cardiovascular System: Part III - Synthesis of Some New Thiobarbituric Acid Derivatives
Sixteen new 1-aryl-3-(2',4',6'-trimethylphenyl)-5-(substituted benzylidene)thiobarbituric Acids (III) have been synthesized by the condensation of appropriate aldehydes with 1-aryl-3-(2',4',6'-trimethylphenyl)thiobarbituric acid (II), and evaluated for their cardiovascular activity in anaesthetized dogs.Some of the compounds exhibit promising hypotensive activity of varying magnitude and duration.
Agarwal, Jagdish C.,Gupta, Y. K.,Bhargava, K. P.,Shanker, K.
p. 714 - 716
(2007/10/02)
More Articles about upstream products of 79838-91-8
Get Best Price for79838-91-8(5E)-5-[(4-chlorophenyl)methylidene]-1-(3-methoxyphenyl)-2-sulfanylide ne-3-(2,4,6-trimethylphenyl)-1,3-diazinane-4,6-dione