Microwave-Assisted Generation and Capture by Azoles of ortho-Quinone Methide Intermediates under Aqueous Conditions
An efficient activator-free protocol for the coupling of o-hydroxybenzyl alcohols and azoles in water has been developed. This C–N bond-formation process is supposed to proceed through an ortho-quinone methide intermediate. A broad range of o-hydroxybenzy
Ether compounds, their use, and intermediates for use in their production
There are disclosed novel ether compounds of the general formula: STR1 wherein R1 is halogen; A is a group of the general formula Q-1: --CH(R2)--(CH2)m --CH (R3)--N(R4)--C(=Y)--X--R5/
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(2008/06/13)
Structure-activity studies on a 1,2,3-triazole derivative, a potent in vitro inhibitor of prostaglandin synthesis: The role of the heterocyclic ring
This paper reports further structural modifications concerning the 1,2,3- triazole ring of the compound A, an effective in vitro inhibitor of prostaglandin synthesis. The introduction of different heterocyclic rings provided further information about of t
A series of 4-substituted phenoxypropanolamines has been prepared and examined for β-adrenoceptor activity.The 4-substituents, di- and triazole ring systems connected to the phenoxy ring by different length chains, were chosen as a means of introducing ca
Machin, Peter J.,Hurst, David N.,Bradshaw, Rachel M.,Blaber, Leslie C.,Burden, David T.,Melarange, Rosemary A.
p. 503 - 509
(2007/10/02)
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