THE PREPARATION OF BILE ACID AMIDES AND OXAZOLINES
Amides obtained by the condensation of some bile acid chlorides with 2-amino-2-methyl-1-propanol on cyclization yield bile acid oxazolines.Physical properties of these bile acid derivatives are described.Some of the oxazolines are non-toxic and are inhibitors of 7-dehydroxylaseactivity in fecal anaerobic bacteria and purified enzymes from these bacteria.
Ayengar, Narayan K. N.,Singhal, Anil K.,McSherry Charles K.,Mosbach, Erwin H.