- SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR
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Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors of Formula (I).
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Paragraph 0380
(2014/02/15)
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- SUBSTITUTED MORPHOLINES AS MODULATORS FOR THE CALCIUM SENSING RECEPTOR
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Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (Ca SR) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (Ca SR) receptors of Formula (I).
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Page/Page column 65
(2012/09/22)
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- Decarboxylation Reaction. X. Introduction of a Carbon unit at the α-Position of Amines by Reaction of Hexahydro-1,3,5-triazines with Carboxylic Acids
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An efficient method for introducing a carbon unit at the α-position of alicyclic amines is described.The method involves the reaction of monocyclic or tetracyclic hexahydro-1,3,5-triazines with trichloroacetic acid, cyanoacetic acid, malonic acid and their derivatives, which are introduced into the α-position of amines in the decarboxylated form.Keywords --- 1,3,5-trialkylhexahydro-1,3,5-triazine; trimer of alicyclic imine; decarboxylation; β-amino acid; carboxylic acid
- Fukawa, Hidemichi,Terao, Yoshiyasu,Achiwa, Kazuo,Sehiya, Minoru
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- INTRODUCTION OF CARBON UNIT AT THE α-POSITION OF ALICYCLIC AMINES UTILIZING A DECARBOXYLATION REACTION WITH MALONIC ACID DERIVATIVES
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A new method for introducing carbon unit at the α-position of alicyclic amines has been exploited.The method involves a reaction of trimers of alicyclic imines with malonic acid derivatives, of which decarboxylation leads to a formation of carbon-carbon bond at the α-position of alicyclic amines.
- Fukawa, Hidemichi,Terao, Yoshiyasu,Achiwa, Kazuo,Sekiya, Minoru
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p. 231 - 232
(2007/10/02)
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