- A new process for preparing flibanserin (by machine translation)
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The invention discloses a new process for preparing of flibanserin. In order to 1 - isopropenyl - 2 - benzimidazolone as raw materials, first with 2 - bromo ethanol reaction, to produce intermediate 1, intermediate 1 generated by the reaction with a sulfo
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Paragraph 0017; 0029; 0030; 0031
(2017/08/29)
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- N-Bridged Heterocycles. Part 5. α,ω-Bis-(2-oxobenzimidazolinyl)-alkanes and -ethers as Selective Ligands for Group-1 and -2 Metals
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A series of the title compounds (10), (12), and (13) and several analogues were synthesised from the readily available 1-isopropenylbenzimidazolin-2-one.Various substituents were attached to the unsubstituted nitrogen atoms of the benzimidazolinone moieties and the series of products obtained were tested for their complexing ability with group-1 and -2 metal-salts.The isolation of crystalline complexes, the solubilisation of the salts in chloroform by ligand, the i.r. carbonyl absorption shift, and the ion-transport ability of the ligand were examined as an index of complexation.Selective complexation, particularly for calcium, was noted in several cases.
- Meth-Cohn, Otto,Smith, David I.
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p. 261 - 270
(2007/10/02)
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