Nucleoside analogues having a ring-open structure, of general formula: STR1 where R and R' may be hydrogen, silyl groups, substituted alkyl groups, benzyl groups and the like, and X is an optionally substituted base such as guanine or adenine, have been s
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(2008/06/13)
Substituted-aza-cytosine compounds and anti-viral uses thereof
Nucleoside analogues having a ring-open structure, of general formula: STR1 where R and R' may be hydrogen, silyl groups, substituted alkyl groups, benzyl groups and the like, and X is an optionally substituted pyrimidine or triazine base, exhibit anti-vi
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(2008/06/13)
Uracil analogues of the acylonucleoside 9--methyl>guanine (BIOLF-62)
A series of substituted uracil analogues of the antiviral agent 9-methyl>guanine (BIOL-62) has been synthesized and characterized.The uracil analogues show little activity against herpesviruses.
Ogilvie, Kelvin K.,Hamilton, Raymond G.,Gillen, Michael F.,Radatus, Bruno K.,Smith, Kendall O.,Galloway, Karen S.
p. 16 - 21
(2007/10/02)
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