Enantioselective Hydrosilylation of Imines Catalyzed by Chiral Zinc Acetate Complexes
A series of zinc acetate complexes with optically pure diphenylethanediamine (DPEDA)-derived ligands have been employed as enantioselective catalyst for the hydrosilylation of various imines. High control of stereoselectivity (up to 97% ee) and excellent yields (up to 96%) were gained for a broad range of N-phosphinoylimines by using (R,R)-N,N′-dibenzyl-1,2-diphenylethane-1,2-diamine. This is the first successful application of an air-stable and environmentally friendly chiral Zn(OAc)2 complex instead of the previously used harmful diethylzinc in the asymmetric reduction of the C=N double bond.
Bez?ada, Agata,Szewczyk, Marcin,Mlynarski, Jacek
p. 336 - 342
(2016/01/15)
Asymmetric transfer hydrogenation of ketimines using well-defined iron(II)-based precatalysts containing a PNNP ligand
Well-defined iron(II)-based complexes containing PNNP ligands catalyze a highly enantioselective reduction of N-(diphenylphosphinoyl)- and N-(p-tolylsulphonyl)-ketimines. Under mild conditions and low catalyst loading, the ketimines are successfully reduced to the corresponding amines in enantiomeric excess ranging from 94 to 99%.
Mikhailine, Alexandre A.,Maishan, Mazharul I.,Morris, Robert H.
p. 4638 - 4641
(2012/10/29)
A Study of the Synthesis of Optically Active Amines from Prochiral N-Phosphinylimines
-
Krzyzanowska, B.,Stec, W. J.
p. 270 - 273
(2007/10/02)
More Articles about upstream products of 82572-09-6