A chemoselective deoxygenation of N-oxides by sodium borohydride-Raney nickel in water
A simple and convenient protocol for deoxygenation of aliphatic and aromatic N-oxides to the corresponding amines in good to excellent yield using sodium borohydride-Raney nickel in water is reported. Other functional moieties such as alkenes, halides, ethers, and amides are unaffected under the present reaction condition.
Gowda, Narendra B.,Rao, Gopal Krishna,Ramakrishna, Ramesha A.
experimental part
p. 5690 - 5693
(2010/11/05)
The effects of alkyl substitution in drugs-I. Substituted dimethylaminoethyl benzhydryl ethers.
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HARMS,NAUTA
p. 57 - 77
(2007/10/05)
Pharmacology of 2-dimethylaminoethyl 2-methylbenzhydryl ether HCI (BS 5930); preliminary report.